resonance energy transfer — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TD0081	EDANS	EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid],1,5-EDANS,EDANS acid [5-((2-Aminoethyl)amino)napht	Others
	EDANS (EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid]) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET).		Others
T11495L	GSK 4027		Others
	GSK 4027 is a PCAF/GCN5 bromodomain chemical probe. In a time-resolved fluorescence resonance energy transfer (TR-FRET) assay, it has a pIC50 of 7.4±0.11 for PCAF.		Others
T81839	MCA succinimidyl ester
	MCA succinimidyl ester, a derivative of MCA, selectively reacts with amines and serves as a peptide substrate for fluorescence resonance energy transfer (FRET) [1].
T81669	NKG2D-IN-2
	NKG2D-IN-2 (compound 47) is an inhibitor of the natural killer group 2D receptor (NKG2D), demonstrating half-maximal inhibitory concentrations (IC50s) of 0.1 µM for NKG2D/MICA and 0.2 µM for ULBP6 in time-resolved fluore...
T78434	Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) TFA
	Mca-(endo-1α-Dap(Dnp))-TNF-α(-5 to +6) amide (human) TFA is a peptide that functions as a fluorescence resonance energy transfer (FRET)-based substrate, with its activity determined by the change in fluorescence intensit...
T78697	Keap1-Nrf2-IN-15
	Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, displaying IC50 values of 77 nM in a fluorescence polarization (FP) assay and 2.5 nM in a time-resolved fluorescence re...
T81838	Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human)
	Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a peptide utilized as a fluorescence resonance energy transfer (FRET) based substrate for proteolytic activity assays, wherein the cleavage-induced change in f...
T78689	HAChE-IN-1
	hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM. Additionally, it inhibits tau-oligomerization with an effective...
T37040	DiIC1(5)	DiIC1(5)
	DiIC1(5) is a signal-off fluorescent probe for the detection of mitochondrial membrane potential disruption. It accumulates in mitochondria and its fluorescence intensity decreases when the mitochondrial membrane potenti...
T81836	Mca-SEVNLDAEFK(Dnp)-NH2
	Mca-SEVNLDAEFK(Dnp)-NH2 is a fluorogenic substrate featuring a 7-methoxycoumarin moiety whose fluorescence is quenched by the adjacent 2,4-dinitrophenyl group through resonance energy transfer. This compound serves as a ...
T78389	Coelenteramine 400a	Bisdeoxycoelenterazine,Coelenterazine 400a
	Coelenteramine 400a (Coelenterazine 400a), a Coelenterazine derivative, serves as a substrate for Renilla luciferase (RLuc), facilitating the emission of blue light at 395 nm [1] [2]. This compound alters the bioluminesc...
T41171	BODIPY FL VH032
	BODIPY FL VH032 is a high-affinity VHL fluorescent probe (Kd= 3.01 nM) with application in time-resolved fluorescence resonance energy-transfer (TR-FRET) assays for high-throughput identification and characterization of ...
T80846	WAAG-3R
	WAAG-3R is a bioactive peptide utilized in an ADAMTS-4 (Aggrecanase-1) assay, where aggrecanases, a subset of the ADAMTS (A disintegrin and metalloprotease with thrombospondin motifs) family, target aggrecan, a key struc...
T83957	CELT-211
	CELT-211 is a potent, selective fluorescent ligand for the h5HT2B serotonin receptor, demonstrating full selectivity over h5HT2A and h5HT2C receptors with a Ki value of 56.3 nM in radioligand binding assays for h5HT2B re...
T83956	CELT-133
	CELT-133 is a selective fluorescent antagonist for the hα1A adrenergic receptor, demonstrating complete selectivity towards α1A over α2A receptors, with a Ki of 5 nM and 15% displacement at 1 μM in radioligand binding as...
T83676	Tianeptine Metabolite MC5 sodium
	Tianeptine metabolite MC5, an active derivative of the atypical antidepressant tianeptine produced through β-oxidation, exhibits selective G protein activation in bioluminescence resonance energy transfer (BRET) assays. ...
T83664	Europium W1024 ITC	Eu-W1024 ITC,Europium W1024 Isothiocyanate
	Europium W1024 isothiocyanate (ITC) is a lanthanide-based fluorophore characterized by its long emission lifetime and significant Stokes shift, featuring excitation and emission maxima at 340 and 613 nm, respectively. Th...
T83952	CoraFluor 1, amine reactive
	CoraFluor 1, an amine-reactive terbium-based compound, serves as a potent donor in time-resolved Förster resonance energy transfer (TR-FRET) assays, including applications in target engagement and ternary complex assessm...
T83959	CELT-426
	CELT-426 is a potent, partially selective fluorescent antagonist of the human D2 dopamine receptor, exhibiting Ki values of 89.3 nM, 194.8 nM, and 263.6 nM for D2, D3, and D4 dopamine receptors, respectively, in radiolig...